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HomeFeline Health ArticlesKidney Failure

Kidney Failure

Kidney Failure - Sudden (Acute) Uremia

Signalment/Description of Pet

Mean Age and Range

Signs/Observed Changes in the Pet


Compounds/Medications That Are Toxic to the Kidneys
  • Ethylene glycol (found in antifreeze); antibiotics (aminoglycosides); antifungal medications (amphotericin B); chemotherapeutic agents (such as cisplatin and doxorubicin); nonsteroidal anti-inflammatory drugs; radiographic contrast agents; heavy metals (such as lead, mercury, arsenic, thallium); insect or snake venom; calcium; grape or raisin ingestion; and lily ingestion (cats)

  • Generalized Disease Affecting the Kidneys
  • Infectious disease (such as leptospirosis or Lyme disease); immune-mediated disease (such as inflammation and accompanying dysfunction of glomeruli [plural of glomerulus] of the kidney [known as “glomerulonephritis”] and inflammation of the arteries [known as “arteritis”]); inflammation of the pancreas (known as “pancreatitis”); generalized disease caused by the spread of bacteria in the blood (known as “septicemia” or “blood poisoning”); blood-clotting disorder (known as “disseminated intravascular coagulopathy” or DIC); liver failure; heat stroke; blood transfusion reactions; bacterial inflammation/infection of the lining of the heart (known as “bacterial endocarditis”); bacterial infection/inflammation of the kidney (known as “pyelonephritis”); and cancer (such as lymphoma; “lymphoma” is a type of cancer that develops from lymphoid tissue, including lymphocytes, a type of white blood cell formed in lymphatic tissues throughout the body)
  • Blockage or obstruction of one or both ureters (the tubes running from the kidneys to the bladder) in cats
  • Risk Factors


    Health Care




    Inadequate Urine Production

    Acid-Base Disorders


    Peritoneal Dialysis or Hemodialysis

    Follow-Up Care

    Patient Monitoring

    Preventions and Avoidance

    Possible Complications

    Expected Course and Prognosis

    Key Points

    • The Pet Health Library contains information on some of the most common medical problems of dogs and cats. This information is designed to assist pet owners in better understanding their pets' health problems.
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    • In the United States, there are millions more owned cats than owned dogs, yet cats visit veterinarians less frequently than dogs. A major reason is that it is very stressful to take cats to the veterinary practice and often owners believe their cat doesn't need routine check-ups for wellness and preventive care. The Cat Friendly Practice® (CFP) program, created by expert feline practitioners, provides a solution to this trend and provides an opportunity for veterinary practices to elevate care for cats and reduce the stress during the visit.
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